High expression of anterior gradient 3 (AGR3) was associated with poor prognosis in luminal B subtype of invasive ductal carcinoma (IDC) patients of grade I-II. (A) Overall survival (OS) and progression-free survival (PFS) curves of 330 cases of IDC patients were shown, respectively. (B) OS and PFS of 236 luminal patients were shown, respectively. (C) OS and PFS of 66 luminal A patients were shown, respectively. (D) OS and PFS of 170 luminal B patients were shown, respectively. (E) OS and PFS of 88 non-luminal patients were shown, respectively. (F) OS and PFS of 61 triple-negative breast cancer (TNBC) patients were shown, respectively. (G) OS and PFS curves of 261 IDC patients of grade Ⅰ-Ⅱ were shown, respectively. (H) OS and PFS of 197 luminal patients of grade Ⅰ-Ⅱ were shown, respectively. (I) OS and PFS of 55 luminal A patients of grade Ⅰ-Ⅱ were shown, respectively. (J) OS and PFS of 142 luminal B patients of grade Ⅰ-Ⅱ were shown, respectively. (K) OS and PFS of 58 non-luminal patients of grade Ⅰ-Ⅱ were shown, respectively. (L) OS and PFS of 40 TNBC patients of grade Ⅰ-Ⅱ were shown, respectively.