Table 1.

ANG II-induced changes in Na⁺ transporter abundance

	D3 ANG II	D14 ANG II
cNHE3 in proximal tubule	1.40	0.78
mNKCC2-P in medullary thick ascending limb	1.04	0.83
Na+-K+-ATPase in medullary thick ascending limb	1.00	0.70
cNKCC2-P in cortical thick ascending limb	1.72	1.74
NCC-P in distal convoluted tubule	1.23	1.93
ENaC in connecting tubule and collecting duct	1.00	1.21
Na+-K+-ATPase in connecting tubule and collecting duct	1.00	1.00

Values are fold changes relative to control, noninfused rats, as measured by Nguyen et al. (29, 30), at 3 days (D3) and 14 days (D14) of angiotensin II (ANG II) treatment. cNHE3, cortical Na⁺/H⁺ exchanger 3; cNKCC2-P/mNKCC2-P, phosphorylated cortical/medullary Na⁺-K⁺-2Cl⁻ cotransporter 2; ENaC: epithelial Na⁺ channel; NCC-P, phosphorylated Na⁺-Cl⁻ cotransporter.