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. 2019 Oct 2;317(6):C1256–C1267. doi: 10.1152/ajpcell.00306.2019

Fig. 7.

Fig. 7.

Human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) electrophysiology changes with time postdifferentiation induction. A: exemplar image of hiPSC-CM clusters cultured on a microelectrode array (MEA). Relationship between spontaneous beating rate (B) and field potential duration (C and D) and the duration of the period postdifferentiation induction. n = 22 MEAs (lines plotted through day 22, 44, and 69 means, since these time points had the most data points). Spontaneous beating rate (E) and field potential duration (F) changes induced by 1 µM isoproterenol (IsoP) in cultures examined at different time points postdifferentiation induction. n = 16–22 MEAs. *P < 0.05, 1-way ANOVA with Holm-Sidak’s multiple comparisons.