Fig. 2.

Twenty-first century analytics of continuous vital sign data to prevent diseases in neonates. This illustration depicts a three-step approach combining: a single or multi-tier analytics of vital signs, b careful clinical assessment, and c auxiliary blood and other imaging studies to prevent and decrease morbidity from life-threatening illnesses. HeRo heart rate characteristics, HRC index heart rate characteristics index, POPS pulse oximetry predictive score, BP blood pressure, CBC complete blood count, CRP C-reactive protein, USG ultrasonography, ABG arterial blood gas, TCM transcutaneous carbon dioxide monitoring, NIRS near-infrared spectroscopy, EEG electroencephalogram, HUS head ultrasound, NEC necrotizing enterocolitis, BPD bronchopulmonary dysplasia, ROP retinopathy of prematurity, IVH intraventricular hemorrhage, MCA Doppler middle cerebral artery Doppler