Fig. 6.

Improvement in the vision guided response in MMP-9 KO mice. Visual function tests were performed with the novel object recognition test (NORT) and the light-dark box test (LDBT) analyses on all three strains of the mice to evaluate their vision and thus ability to navigate their paths under different testing conditions. Representative images showing vision guided behavior as the discrimination index via NORT (A, B) and the transfer latency time via LDBT (C). Data values are means ± SE of 4–6 separate experiments; *P < 0. 0001 compared with C57BL/6J, #P < 0. 0001 compared with FVB/NJ, ## P < 0. 05 compared with FVB/NJ.