Table 2.
Top 10 upregulated and downregulated mRNAs in advanced atherosclerotic plaques compared with normal arterial intimae
| Seqname | Gene Symbol | Regulation | P Value | Absolute Fold Change | Regulation | RNA Length | Chromosome | Strand |
|---|---|---|---|---|---|---|---|---|
| NM_001040060 | SPP1 | up | 8.48553E-08 | 7316.686689 | up | 1560 | chr4 | + |
| NM_002423 | MMP7 | up | 4.05031E-05 | 762.442449 | up | 1147 | chr11 | − |
| NM_018643 | TREM1 | up | 1.98707E-06 | 606.5559703 | up | 1633 | chr6 | − |
| ENST00000368738 | S100A9 | up | 1.29326E-07 | 255.8468333 | up | 577 | chr1 | + |
| NM_001001548 | CD36 | up | 8.96768E-08 | 250.779817 | up | 4727 | chr7 | + |
| NM_138461 | TM4SF19 | up | 2.73667E-05 | 223.2345985 | up | 1077 | chr3 | − |
| NM_001444 | FABP5 | up | 4.33327E-10 | 210.793027 | up | 751 | chr8 | + |
| NM_152565 | ATP6V0D2 | up | 5.68548E-06 | 177.0426041 | up | 2370 | chr8 | + |
| NM_003467 | CXCR4 | up | 1.88792E-06 | 171.8156451 | up | 1691 | chr2 | − |
| NM_001276 | CHI3L1 | up | 5.398E-09 | 161.2576396 | up | 1867 | chr1 | − |
| NM_001146312 | MYOCD | down | 4.15082E-07 | 388.0686464 | down | 6950 | chr17 | + |
| NM_182826 | SCARA3 | down | 1.66378E-07 | 347.4284531 | down | 1711 | chr8 | + |
| NM_203371 | FIBIN | down | 9.53543E-08 | 270.8993334 | down | 3024 | chr11 | + |
| NM_001017398 | TRIM36 | down | 2.14195E-08 | 269.141173 | down | 906 | chr5 | − |
| NM_001608 | ACADL | down | 2.62191E-06 | 236.8372231 | down | 2565 | chr2 | − |
| ENST00000377694 | IGFBPL1 | down | 3.15538E-06 | 224.5009801 | down | 1093 | chr9 | − |
| NM_002474 | MYH11 | down | 6.73347E-09 | 213.8021672 | down | 6882 | chr16 | − |
| NM_024686 | TTLL7 | down | 3.30751E-07 | 187.8536755 | down | 3648 | chr1 | − |
| NM_170734 | BDNF | down | 3.24577E-05 | 183.3155043 | down | 3976 | chr11 | − |
| NM_053027 | MYLK | down | 8.07202E-07 | 183.1613974 | down | 7699 | chr3 | − |