Table 2.

Arterial blood variables during throughout the 20-min hypoxia exposure

Variables and Time, mins	Control	High-Affinity Hb
$\text{P}{\text{a}}_{\text{O}}{}_{{}_2}$, mmHg
Baseline	90 ± 2	85 ± 3
5	49 ± 1	47 ± 1
12	48 ± 1	48 ± 1
20	48 ± 1	48 ± 1
$\text{P}{\text{a}}_{\text{C}\text{O}}{}_{{}_2}$, mmHg
Baseline	40 ± 1	39 ± 1
5	40 ± 1	39 ± 0
12	40 ± 1	39 ± 0
20	40 ± 1	39 ± 0
pH
Baseline	7.40 ± 0.004	7.41 ± 0.005
5	7.41 ± 0.004	7.41 ± 0.006
12	7.41 ± 0.004	7.41 ± 0.006
20	7.40 ± 0.005	7.41 ± 0.004
Lac, mmol/L
Baseline	0.5 ± 0.1	0.6 ± 0.0
5	0.5 ± 0.1	0.6 ± 0.0
12	0.5 ± 0.1	0.6 ± 0.0
20	0.5 ± 0.0	0.6 ± 0.0
$\text{S}{\text{a}}_{{\text{O}}_2}$, %
Baseline	95 ± 0	97 ± 0*
5	83 ± 1	92 ± 1*
12	83 ± 1	92 ± 1*
20	82 ± 1	92 ± 1*
$\text{C}{\text{a}}_{\text{O}}{}_{{}_2}$, ml/dL
Baseline	17.7 ± 0.4	24.9 ± 0.9*
5	15.4 ± 0.4	23.6 ± 0.9*
12	15.2 ± 0.5	23.7 ± 0.9*
20	15.2 ± 0.5	23.6 ± 0.9*

Values are means ± SE. $\text{P}{\text{a}}_{\text{O}}{}_{{}_2}$, arterial oxygen tension; $\text{P}{\text{a}}_{\text{C}\text{O}}{}_{{}_2}$, arterial carbon dioxide tension; Lac, arterial lactate concentration; $\text{S}{\text{a}}_{{\text{O}}_2}$, arterial oxyhemoglobin saturation; $\text{C}{\text{a}}_{\text{O}}{}_{{}_2}$, arterial oxygen content.

^*P < 0.05, significantly different from control.