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Stimulation of the vagus nerve evoked equivocal changes in heart rate (HR) in control and db/db mice. A: representative tracings of the HR response to vagal stimulation in anesthetized control and db/db mice. B: summary data showing the mean change in HR. There was no difference between control and db/db mice. C: time required for the maximum bradycardic response was less in db/db mice at 10 Hz and 20 Hz. Control: n = 5 animals; db/db: n = 5 animals. ***P ≤ 0.003; BPM, beats/min.
