Table 4.
Semi quantitative scoring of the histopathology in the liver of Clarias gariepinus exposed to silver nanoparticles and silver nitrate for 15 days exposure and 15 days recovery periods (N = 3).
| Histopathologic lesion | C | AgNO3 (100 μg/L) | 20 nm/10 μg/L AgNPs | 20 nm/100 μg/L AgNPs | 40 nm/10 μg/L AgNPs | 40 nm/100 μg/L AgNPs |
|---|---|---|---|---|---|---|
| Exposure | ||||||
| Infiltrations of inflammatory cell | – | ++ | + | ++ | + | + |
| Melanomacrophage aggregation | – | ++ | + | ++ | + | ++ |
| Dilation of blood vessel | – | – | + | – | – | – |
| Hepatic necrosis | – | ++ | + | ++ | ++ | ++ |
| Central vein dilation | – | + | + | + | + | + |
| Hemorrhage | – | + | + | + | + | + |
| Recovery | ||||||
| Infiltrations of inflammatory cell | – | – | – | + | + | – |
| Melanomacrophage aggregation | – | – | – | + | – | – |
| Dilation of blood vessel | – | – | – | – | – | – |
| Hepatic necrosis | – | – | + | + | + | – |
| Central vein dilation | – | – | – | + | + | – |
| Hemorrhage | – | – | – | + | – | – |
Score: (-) No alteration, (+) Mild alteration, (++) moderate alteration, (+++) severe alteration.
C = control, AgNPs = silver nanoparticles and AgNO3= silver nitrate.