. 2020 Jan 8;17:100518. doi: 10.1016/j.conctc.2020.100518

Table 1.

Study schedule.

	Visit 0 (screening) V0	Visit 1 (baseline) V1	Visit 2 V2	Visit 3 V3	Visit 4 V4	Visit 5 V5	Visit 6 V6	Visit 7 Follow-up V7
Assessments		≤7 days after V0	1 week after V1 ± 3 days	2 weeks after V1 ±3 days	4 weeks after V1 ±3 days	8 weeks after V1 ±7 days	12 weeks after V1 ±7 days	24 weeks after V1 ±7 days
Medical Hx	X
Tobacco/vaping products Hx	X
Eligibility criteria checks	X
Step Test Training (10–15 min)	X
Instructions for urine collection and storage; provision of containers	X			X
Patient Information Sheet	X
Informed consent		X
Randomization		X
Device Familiarization (30–60 min)		X
Dispense Device (plus 1 wk supply of tobacco sticks for iQOS or liquid for JustFog)		X
Dispense 1 wk supply of tobacco sticks for iQOS or liquid for JustFog			X
Dispense 2 wk supply of tobacco sticks for iQOS or liquid for JustFog				X
Dispense 4 wk supply of tobacco sticks for iQOS or liquid for JustFog					X	X
Cigarette/day	X	X	X	X	X	X	X	X
eCO	X	X	X	X	X	X	X	X
Vital Signs (BP, HR)		X	X	X	X	X	X	X
Weight and height		X					X	X
Urine sample processing		X			X
Product use recording			X	X	X	X	X	X
Product use checks (collect used and unused tobacco sticks and liquid refill containers)			X	X	X	X	X	X^a
mCEQ					X	X	X	X^a
Smoking Cue Appeal		X			X	X	X	X^a
ITUQ					X	X	X	X^a
Risk perception questionnaires (PRI-P CC; PRI-P RRP)		X			X	X	X	X^a
EQ-VAS		X			X		X	X
Step test		X			X		X	X
Safety reporting/AEs		X	X	X	X	X	X	X^a
Product failure reporting			X	X	X	X	X	X^a

if appropriate (i.e. only if participants were still using the same products of the study).