Table 1.

Prediction of the free energy of small molecule G6P and D2-G6P binding (kcal/mol) by wild-type and mutant MondoA.

Mutants	G6P	D2-G6P
WT	−38.25	−16.35
GKL139-141GAA	−33.13	−13.00
DEL139-141	−21.99	−0.78
S282G	−38.47	−16.67
S287A	−33.17	−14.29
T284A	−36.54	−16.18