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. 2019 Apr 27;7(1):18–23. doi: 10.1016/j.ajur.2018.12.009

Table 1.

The main data of articles reporting outcomes of tissue-engineered urethroplasty using cultured epithelial cells in humans.

Reference in the text Journal year Type of cells Site of original cells No. of patients Urethral Pathology Site of strictures Success rate (%) Mean follow-up
Romagnoli et al. [1] New Engl J Med 1990 Urethral External  urinary meatus 2 Hypospadias 100 18 months
Romagnoli et al. [11] J Urol 1993 Urethral External  urinary meatus 8 Hypospadias 100 18 months
Raya-Rivera et al. [12] Lancet 2011 Bladder  urothelium Bladder 5 Traumatic  strictures Posterior urethra 90 71 months
Fossum et al. [13] Acta Paediatrica 2012 Bladder  urothelium Bladder 6 Hypospadias 100 7.25 years
Bhargava et al. [14] Eur Urol 2008 Oral mucosa Mouth 5 Lichen  sclerosus  strictures Anterior urethra 0 33.6 months
Ram-Liebig et al. [15] EBioMedicine 2017 Oral mucosa Mouth 99 Urethral  strictures Anterior urethra 85 24 months