Table 1.
The main data of articles reporting outcomes of tissue-engineered urethroplasty using cultured epithelial cells in humans.
| Reference in the text | Journal year | Type of cells | Site of original cells | No. of patients | Urethral Pathology | Site of strictures | Success rate (%) | Mean follow-up |
|---|---|---|---|---|---|---|---|---|
| Romagnoli et al. [1] | New Engl J Med 1990 | Urethral | External urinary meatus | 2 | Hypospadias | 100 | 18 months | |
| Romagnoli et al. [11] | J Urol 1993 | Urethral | External urinary meatus | 8 | Hypospadias | 100 | 18 months | |
| Raya-Rivera et al. [12] | Lancet 2011 | Bladder urothelium | Bladder | 5 | Traumatic strictures | Posterior urethra | 90 | 71 months |
| Fossum et al. [13] | Acta Paediatrica 2012 | Bladder urothelium | Bladder | 6 | Hypospadias | 100 | 7.25 years | |
| Bhargava et al. [14] | Eur Urol 2008 | Oral mucosa | Mouth | 5 | Lichen sclerosus strictures | Anterior urethra | 0 | 33.6 months |
| Ram-Liebig et al. [15] | EBioMedicine 2017 | Oral mucosa | Mouth | 99 | Urethral strictures | Anterior urethra | 85 | 24 months |