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XIST knockdown ameliorates Aβ25-35-induced toxicity in hippocampal neurons. Hippocampal neurons were treated with control, 25 μM Aβ25-35, si-control+25 μM Aβ25-35, and si-XIST+25 μM Aβ25-35, and then used for morphologic observation (A), cell viability (B), LDH release (C), and K+ leakage (D) determination. *P < 0.05.
