Table 4.
Univariate and multivariate analyses of survival in gastric cancer
| Variable | Patients (n) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
|
|
|
||||
| HR (95% CI) | P | HR (95% CI) | P | ||
| Age | 0.806 (0.493-1.317) | 0.389 | |||
| <60 | 74 | ||||
| ≥60 | 76 | ||||
| Gender | 0.614 (0.359-1.049) | 0.074 | |||
| Male | 93 | ||||
| Female | 57 | ||||
| Tumor size | 1.455 (0.886-2.389) | 0.138 | |||
| <5 cm | 71 | ||||
| ≥5 cm | 79 | ||||
| Histological grade | 1.701 (0.964-3.002) | 0.067 | |||
| Well and moderate | 47 | ||||
| Poor and others | 103 | ||||
| Tumor location | 0.786 (0.575-1.075) | 0.132 | |||
| Upper | 24 | ||||
| Middle | 51 | ||||
| Lower | 75 | ||||
| Depth of invasion | 3.807 (1.87-7.747) | <0.0001 | |||
| T1+T2 | 45 | ||||
| T3+T4 | 105 | ||||
| Lymph node metastasis | 2.395 (1.372-4.183) | 0.002 | |||
| Absent | 58 | ||||
| Present | 92 | ||||
| TNM stage | 3.139 (1.748-5.635) | <0.0001 | 0.35 (0.194-0.63) | <0.0001 | |
| I-II | 59 | ||||
| III-IV | 91 | ||||
| FAM3C expression | 0.346 (0.176-0.678) | 0.002 | 0.393 (0.199-0.773) | 0.007 | |
| High | 105 | ||||
| Low | 45 | ||||
| PDGFR expression | 0.5 (0.297-0.842) | 0.009 | |||
| High | 79 | ||||
| Low | 71 | ||||
| E-cadherin expression | 1.52 (0.902-2.56) | 0.116 | |||
| High | 60 | ||||
| Low | 90 | ||||
| Vimentin expression | 0.481 (0.274-0.843) | 0.011 | |||
| Positive | 28 | ||||
| Negative | 122 | ||||
CI, Confidence interval; HR, Hazard ratio.