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. 2018 Jul 1;11(7):3247–3256.

Figure 4.

Figure 4

(A) NaHS promotes expression of MMP-2 and MMP-9 in EC109 cells. (B and C) EC109 cells were treated with NaHS (500 µmol/L) for 6, 12, and 24 h. AG490 suppresses the NaHS-induced increase in the expression of MMP-2 and MMP-9 in EC109 cells. EC109 cells were treated with NaHS (500 µmol/L) and AG490 (60 µmol/L) for 24 h. The protein levels of MMP-2 and MMP-9 were evaluated by western blot analysis. Data are shown as the mean ± SEM (n=3). **P<0.01 versus control group; ++P<0.01 versus NaHS group.