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Function of Munc18b. A-D: qRT-PCR and Western blot assay show Munc18b mRNA and protein levels in HBE16 cells transfected with si-Munc18b, pcDNA-Munc18b, or their respective controls. E and F: ELISA shows that Munc18b knockdown significantly inhibits IL-13-induced MUC5AC secretion, and Munc18b overexpression obviously aggravates MUC5AC secretion induced by IL-13. *P < 0.05 and **P < 0.01.
