Figure 4.

miR-148a suppresses pancreatic cancer cells proliferation, migration and invasion by targeting GLUT1. A: MTT assay was used to detect the function of miR-148a on proliferation of two pancreatic cancer cell lines. The growth rates expressed as a percentage of the control. B: The classic transwell assay to examine the function of miR-148a on migration of pancreatic cancer cells. C: The Matrigel invasion assay was employed to investigate the function of miR-148a on pancreatic cancer cells. The results were analyzed by student t-test and P<0.05 was considered as statistically significant. *P<0.05, **P<0.01.