Figure 3.

Knockdown of ROR1 inhibits lung adenocarcinoma cell invasion. Transwell invasion assay was performed in PC9, PC9erlo and NCI-H1975 cells. The three cell lines were transfected with siROR1 for 48 h and then plated into 24-well chambers. Invasive cells were stained with crystal violet 24 h later and observed using a microscope (magnification, 100×). Three independent experiments were performed for quantification. Mock, wild-type cells; siNC, negative control small interfering RNA-transfected cells; siROR1, ROR1 siRNA-transfected cells.