Table 5.
Comparison of miRNAs relative expression between cardiotoxicity patients and non-cardiotoxicity patients
| miRNAs | Cardiotoxicity patients (N=9) | Non-cardiotoxicity patients (N=170) | P value |
|---|---|---|---|
| Let-7b | 1.051 (0.396-1.788) | 1.129 (0.564-1.720) | 0.810 |
| Let-7f | 0.408 (0.176-0.689) | 1.124 (0.604-2.249) | 0.001 |
| miR-17-5p | 0.642 (0.465-1.450) | 1.060 (0.682-1.671) | 0.332 |
| miR-17-3p | 1.302 (0.696-2.692) | 1.355 (0.649-2.195) | 0.771 |
| miR-18a | 1.039 (0.380-1.914) | 1.181 (0.619-1.960) | 0.535 |
| miR-19a | 0.853 (0.464-1.800) | 2.100 (0.987-3.298) | 0.023 |
| miR-19b-1 | 0.485 (0.172-1.756) | 1.358 (0.644-2.038) | 0.083 |
| miR-20a | 0.727 (0.518-0.920) | 1.175 (0.524-2.025) | 0.040 |
| miR-92a | 0.883 (0.572-1.265) | 1.294 (0.655-1.786) | 0.160 |
| miR-126 | 0.559 (0.416-1.165) | 1.594 (0.748-2.744) | 0.020 |
| miR-130a | 3.183 (1.572-5.371) | 2.970 (1.714-4.921) | 0.815 |
| miR-210 | 0.591 (0.326-1.231) | 1.218 (0.642-2.056) | 0.032 |
| miR-296 | 0.668 (0.361-1.041) | 0.678 (0.403-1.411) | 0.853 |
| miR-378 | 0.645 (0.371-1.159) | 1.036 (0.535-1.790) | 0.104 |
Data were presented as median (25th-75th quantiles). Comparison was determined by a Wilcoxon rank sum test. P value <0.05 was considered significant.