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. 2018 Oct 1;11(10):4784–4794.

Figure 4.

Figure 4

α-SMA, CTGF, TGF-β1, Smad3 and Smad7 protein and mRNA levels of each group. (A) The western blot bands of α-SMA, CTGF, TGF-β1, Smad3 and Smad7. (B-E) The protein and mRNA expression levels of α-SMA, CTGF, TGF-β1 and Smad3 in the obese group were higher than those in the control group, and the expression level of Smad7 was lower than in (F) the control group. Octreotide treatment significantly decreased α-SMA, Smad3, CTGF, and TGF-β1 protein and mRNA expression levels in obese rats. The Smad7 protein and mRNA expression level increased in the octreotide treatment group. Values are expressed as mean ± standard deviation. *P<0.05, **P<0.01 vs. the control group; #P<0.05, ##P<0.01 vs. the HFD group. α-SMA, α-smooth muscle actin; CTGF, connective tissue growth factor; TGF-β1, transforming growth factor-β1.