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. 2018 Sep 1;11(9):4374–4384.

Figure 4.

Figure 4

miR-223 induces EMT of NPC cells by suppressing SSRP1 expression. The transfections of 5-8F cells were divided in four groups: Group A, transfection with negative control siRNA; Group B, transfection with miR-223 mimics; Group C, co-transfection with the miR-223 mimics and SSRP-siRNA-810; Group D, transfection with SSRP1-siRNA-810. A Western blot assay was performed after the cell transfections. A. A Western blot analysis revealed the effects of miR-223 and SSRP1 on EMT-relative protein expression. B. The effects of miR-223 and SSRP1 on E-cadherin expression. C. The effects of miR-223 and SSRP1 on N-cadherin expression. D. The effects of miR-223 and SSRP1 on Vimentin expression. Error bars represent ± S.E. and *P < 0.05 versus NC. &P < 0.05 versus miR-223 group.