Table 3.

Haplotype frequencies and their association with tuberculosis risk

Gene	SNPs	Haplotype	Frequency		OR (95% CI)	P a
			Case	Control
IL-1α	rs3783550	GGGGA	0.575	0.667	1.00	---
	rs3783546	TCATG	0.293	0.242	1.47 (1.11-1.94)	0.007*
	rs2856838	TCGTG	0.113	0.091	1.42 (0.97-2.08)	0.070
	rs1609682
	rs3783521
IL-1β	rs2853550	GT	0.474	0.530	1.00	---
	rs1143643	GC	0.436	0.378	1.30 (1.02-1.67)	0.034*
		AC	0.090	0.092	1.10 (0.75-1.62)	0.630
IL-1β	rs1143630	GAGG	0.432	0.537	1.00	---
	rs1143627	GGAG	0.324	0.220	1.86 (1.40-2.46)	< 0.0001*
	rs16944	TGAG	0.159	0.149	1.37 (0.96-1.95)	0.081
	rs1143623	GGAC	0.077	0.081	1.17 (0.76-1.80)	0.480

OR = odds ratio; 95% CI = 95% confidence interval.

^* P < 0.05 indicates statistical significance;

^a p vsalue were calculated by unconditional logistic regression.