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. 2018 Nov 1;11(11):5203–5212.

Figure 5.

Figure 5

SIRT1 was targeted by miR-30a-5p. A. The putative binding sites of miR-30a-5p in the 3’UTR of SIRT1 was predicted using the online software program Targetscan, as well as the mutant in SIRT1 3’UTR. B. Luciferase reporter assay revealed the inhibitory effect of miR-30a-5p on the activity of SIRT1. C, D. The expressions of SIRT1 mRNA and protein in the miR-30a-5p-overexpressed or inhibited 3T3-L1 cells were detected by RT-qPCR or WB assay. *P < 0.05, compared with the NC or the anti-NC group.