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IHC analysis of SphK1 expression in representative pericarcinoma (normal) and CRC tissues (×400). A. No expression in pericarcinoma colorectal cells; B. Positive expression in the cytoplasm of colorectal tubular adenocarcinoma cells; C. Positive expression in colorectal mucinous adenocarcinoma cells; D. Positive expression in the cytoplasm of undifferentiated colorectal carcinoma cells.
