Table 3.
Robo1 expression in human cancers and related non-neoplastic diseases
| Organ | Histological type | Positivity | Staining | % |
|---|---|---|---|---|
| Skin | Squamous cell carcinoma | 13/13 | +++ | 100 |
| Uterine cervix | Squamous cell carcinoma | 11/11 | +++ | 100 |
| Esophagus | Sqaumous cell carcinoma | 13/13 | +++ | 100 |
| Adenocarcinoma | 0/4 | - | 0 | |
| Lung | Squamoua cell carcinoma | 27/39 | ++ | 70 |
| Adenocarcinoma | 3/16 | -~± | 17.8 | |
| Small cell carcinoma | 3/5 | -~+ | 60 | |
| Large cell carcinoma | 0/4 | - | 0 | |
| Carcinoid | 4/4 | ++ | 100 | |
| Liver | Hepatocellular carcinoma | 22/28 | -~+++ | 78.6 |
| Cirrhosis | 0/10 | - | 0 | |
| Hepatitis | 0/10 | - | 0 | |
| Breast | Ductal carcinoma | 11/44 | -~+ | 25 |
| Kidney | Renal cell carcinoma | 0/16 | - | 0 |
| Pancreas | Adenocarcinoma | 8/35 | -~± | 22.9 |
| Colon | Adenocarcinoma | 5/35 | -~± | 14.3 |
| Ovary | Adenocarcinoma | 3/36 | -~± | 8.3 |
| Stomach | Adenocarcinoma | 1/11 | -~± | 9 |
-: negative, ±: weakly positive, +: positive, ++: moderately positive, +++: strongly positive.