Table 4.
Immunohistochemical expression of Robo1 and glypican by HCC
| No. | Differentiation of HCC | Age | Sex | Background | Virus | Glypican staining | Robo1 staining |
|---|---|---|---|---|---|---|---|
| 1 | Poor | 74 | M | LC | C | + | +++ |
| 2 | Poor | 49 | M | LC | B | + | +++ |
| 3 | Poor | 76 | M | LF | C | - | +++ |
| 4 | Poor | 71 | F | AIH | - | ++ | +++ |
| 5 | Poor moderate | >59 | M | CAH | B | + | +++ |
| 6 | Poor moderate | >71 | F | LC | C | ++ | +++ |
| 7 | Moderate~poor | 62 | M | LC | B | - | ++ |
| 8 | Moderate~poor | 63 | M | LF | B | - | +++ |
| 9 | Moderate~poor | 55 | F | LC | B | ++ | ++ |
| 10 | Moderate~poor | 55 | M | LC | B | ±~+ | +++ |
| 11 | Moderate~poor | 69 | M | LC | NBNC | - | + |
| 12 | Moderate | 76 | F | LF | C | + | +++ |
| 13 | Moderate | 80 | M | Lc | C | ++ | +++ |
| 14 | Moderate | 60 | F | LC | C | + | +++ |
| 15 | Moderate | 70 | F | LC | C | + | +++ |
| 16 | Moderate | 70 | F | LC | C | - | +++ |
| 17 | Moderate | 46 | M | LC | C | ++ | + |
| 18 | Moderate | 73 | F | LC | C | ++ | + |
| 19 | Moderate | 65 | M | LC | C | -~± | +++ |
| 20 | Moderate | 70 | M | LF | NBNC | - | +++ |
| 21 | Well~moderate | 50 | M | CAH | B | - | -~+++ |
| 22 | Well | 71 | M | B | C | ++ | - |
| 23 | Well | 62 | M | C | C | - | - |
| 24 | Well | 81 | M | C | C | ND | - |
| 25 | Well | 71 | M | C | C | - | - |
| 26 | Well | 67 | M | C | C | - | - |
| 27 | Well | 71 | M | C | C | - | -~+++ |
| 28 | Well | 66 | M | C | C | - | -~+++ |
LC: Liver cirrhosis, LF: Liver fibrosis, CAH: Chronic active hepatitis, AIH: Autoimmune hepatitis, NBNC: non-B non-C, ND: not done, -: negative, ±: positive, +: positive, ++: moderately positive, +++: strongly positive.