Table 2.
Decreased brain activity and gray matter volume in premenopausal women vs menopausal women
| Brain areas | t-value | Degrees of freedom | MNI coordinates |
Laterality | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Decreased brain activity | ||||||
| Parahippocampal gyrus | 3.34 | 36 | –32 | 8 | –26 | Lt, 90.4% |
| Head of caudate nucleus | 2.93 | 36 | 22 | 21 | 4 | Rt, 100.0% |
| Insula | 2.78 | 36 | 48 | –6 | 2 | Rt, 84.9% |
| Putamen | 2.77 | 36 | 22 | 20 | 1 | Rt, 100.0% |
| Hippocampus | 2.77 | 36 | –10 | –4 | –19 | N, 50.0% |
| Hypothalamus | 2.68 | 36 | –4 | –2 | –14 | Lt, 85.2% |
| Amygdala | 2.54 | 36 | –30 | 5 | –24 | Lt, 100.0% |
| Globus pallidus | 2.50 | 36 | 22 | 2 | 3 | Rt, 83.3% |
| Decreased gray matter volume | ||||||
| Insula | 10.26 | 36 | –38 | 4 | 7 | Lt, 68.1% |
| Putamen | 7.27 | 36 | –34 | –3 | 5 | Lt, 100.0% |
| Parahippocampal gyrus | 6.72 | 36 | –30 | 9 | –24 | Lt, 100.0% |
| Amygdala | 6.49 | 36 | –31 | 8 | –21 | Lt, 75.9% |
| Anterior cingulate cortex | 5.80 | 36 | –1 | 42 | 19 | Lt, 79.3% |
Lt = left dominant hemisphere; MNI = Montreal Neurological Institute; N = non-dominant hemisphere; Rt = right dominant hemisphere.