Table I.
Demographic and basic parameters of the patient cohort at enrollment
| Parameters | Non-survivors (total n = 156) | Survivors (total n = 413) | P-value |
|---|---|---|---|
| Age (n = 114 vs. 381) | 72.87 ±0.87 | 64.37 ±0.65 | < 0.01 |
| Gender (n; female/male) | 53/103 | 110/303 | 0.096 |
| BMI (n = 97 vs. 322) | 27.03 ±0.55 | 27.60 ±0.26 | 0.32 |
| GGT (n = 156 vs. 411) | 70.54 ±9.0 | 46.20 ±2.50 | < 0.01 |
| AST (n = 155 vs. 413) | 161.63 ±41.72 | 66.05 ±5.64 | < 0.01 |
| ALT (n = 156 vs. 413) | 93.07 ±24.43 | 39.50 ±3.14 | < 0.01 |
| Bilirubin (n = 152 vs. 385) | 0.65 ±0.03 | 0.65 ±0.02 | 0.95 |
| CRP (n = 152 vs. 401) | 4.72 ±0.51 | 1.58 ±0.14 | < 0.01 |
| Creatinine (n = 154 vs. 407) | 1.64 ±0.08 | 1.33 ±0.04 | < 0.01 |
| Urea (n = 154 vs. 406) | 29.48 ±1.34 | 20.47 ±0.74 | < 0.01 |
| eGFR (n = 113 vs. 378) | 49.60 ±1.87 | 61.41 ±0.91 | < 0.01 |
| Troponin (n = 155 vs. 408) | 13.28 ±2.32 | 7.58 ±0.98 | < 0.01 |
| Myoglobin (n = 146 vs. 381) | 639.29 ±132.78 | 301.60 ±31.97 | < 0.01 |
| STEMI | 27 (26.7%)1 | 91 (27.5%)1 | 1F |
| NSTEMI | 74 (73.3%)1 | 240 (72.5%)1 | |
| Ex-/smoker (n = 100 vs. 324) | 12/15 (12%/15%) | 80/92 (24.7%/28.4%) | χ2: < 0.01 |
| Type 2 diabetes | 28 (27.7% of n = 101) | 108 (33.4% of n = 323) | 0.3F |
| Hypercholesterolemia | 73 (73% of n = 100) | 272 (83.6% of n = 325) | 0.0196F |
| RR systolic (n = 97 vs. 324) | 127.4 | 134.6 | 0.01 |
| RR diastolic (n = 97 vs. 324) | 63.4 | 66.3 | 0.1 |
| Heart rate (n = 80 vs. 284) | 80.9 | 75.9 | 0.06 |
| Family history | 18 (18.2% of n = 99) | 108 (33.5% of n = 322) | < 0.01F |
Continuous data are presented as mean ± SEM, categorical data as absolute numbers. Comparison between survivors and non-survivors by Student’s t test (continuous data) and Fisher’s exact test/χ2 (categorical data). ALT – alanine transaminase, AST – aspartate transaminase, BMI – body mass index, CRP – C-reactive protein, eGFR – estimated glomerular filtration rate, GGT – γ-glutamyl transferase.
1
Percentages of 101 non-survivors and of 331 survivors with known STEMI/NSTEMI
F
tested with Fisher’s exact test.