. 2019 Nov 27;9(4):205. doi: 10.3390/diagnostics9040205

Table 4.

Biochemical parameters.

Time Points	Weight [g]		ALT [U/L]		HOMA-IR
Time Points	CONTROL	HFHCh	CONTROL	HFHCh	CONTROL	HFHCh
2 weeks	401.66 ± 10.57	400 ± 14.14	18.8 * ± 0.06	26.6 * ± 0.73	0.69 ± 0.25	1.02 ^5,6 ± 0.46
4 weeks	380.83 ± 17.89	424.16 ± 32.07	19.4 * ± 0.09	24.8 * ± 0.18	0.95 * ± 0.31	1.30 * ± 0.41
8 weeks	408.33 ± 10.67	420.83 ± 16.69	18.2 * ± 0.04	23.6 * ± 0.26	0.48 * ± 0.10	1.48 * ± 0.53
12 weeks	420.00 * ± 12.90	463.33 *^1,2,3 ± 11.05	19.0 * ± 0.05	22.7 * ± 0.29	0.73 * ± 0.215	1.30 * ± 0.70
16 weeks	418.33 * ± 13.44	477.50 *^1,2,3 ± 19.09	18.4 * ± 0.07	30.4 * ± 0.57	0.66 * ± 0.32	1.71 * ± 0.48
20 weeks	420.00 * ± 16.33	496.67 *^1,2,3 ± 17.95	18.3 * ± 0.92	27.9 * ± 0.49	0.69 * ± 0.38	2.07 * ± 0.72
Time Points	CHOLESTEROL [mg/dL]		TNF-α [pg/mL]		LPS [ng/mL]
Time Points	CONTROL	HFHCh	CONTROL	HFHCh	CONTROL	HFHCh
2 weeks	60.47 * ± 17.65	101.24 *^,5,6 ± 19.77	122.34 ± 9.49	149.51 ^5,6 ± 17.62	1.47 ± 1.88	2.62 ^5,6 ± 2.59
4 weeks	64.77 * ± 6.07	111.31 *^,5,6 ± 14.66	118.6 * ± 6.19	142.53 ^5,6 * ± 20.57	2.17 ± 1.61	2.57 ^5,6 ± 2.00
8 weeks	46.13 * ± 22.79	112.38 *^,5,6 ± 16.54	124.30 * ± 7.12	136.74 *^,5,6 ± 10.41	1.48 ± 1.84	2.71 ^5,6 ± 0.98
12 weeks	49.10 * ± 12.41	121.52 *^,5,6 ± 19.77	125.41 * ± 13.26	141.11 *^,5,6 ±16.51	2.03 * ± 2.84	3.37 *⁶ ± 3.32
16 weeks	68.48 * ± 15.60	185.79 *^,1,2,3,4 ± 29.92	124.14 * ± 17.40	165.34 *^,1,2,3,4,6 ± 16.12	1.77 * ± 1.47	3.97 *^,1,2,3,6 ± 2.17
20 weeks	72.63 * ± 11.66	203.16 *^,1,2,3,4 ± 64.42	129.13 * ± 18.12	241.58 *^,1,2,3,4,5 ± 98.49	2.33 * ± 1.91	8.82 *^,1,2,3,4,5,6 ± 3.25

* p < 0.05 between the control and non-alcoholic fatty liver disease (NAFLD) group, p < 0.05 between particular subgroup: ¹—2 weeks, ²—4 weeks, ³—8 weeks, ⁴—12 weeks, ⁵—16 weeks, ⁶—20 weeks. LPS— lipopolysaccharides.