Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Sep 28;7(4):133. doi: 10.3390/vaccines7040133

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Histopathological analysis shows differential lung pathology on Day 14 post challenge dependent on influenza virus and vaccination history. Respiratory tissue was collected from ferrets Day 14 post challenge and the lungs were processed for histopathological assessment. Tissue morphology was assessed by hematoxylin & eosin staining. Lungs were analyzed by microscopy from at least three ferrets per group. Images were captured as described and representative images from the groups Naïve-Mock Vac; PreUSSR-Mock Vac; and PreUSSR-2x Vac are shown. High resolution scans were performed using an Aperio ScanScope XT (Leica Biosystems, Concord, Canada) at 40× magnification. Images of the scans were captured using the HALO program from UHN AOMF (Advanced Optical Microscopy Facility, Toronto, Canada) at 5× (low) or 20× (high) magnification of the scan.