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. 2019 Nov 12;8(4):231. doi: 10.3390/pathogens8040231

Figure 3.

Figure 3

ChAdOx1 Chik and ChAdOx1 Chik ΔCap vaccines prevent weight loss of A129 mice following CHIKV-LR challenge. (a) The percentages of weight change after the challenge for each vaccine are shown. Data are represented as means and SEMs. Restricted maximum likelihood mixed model with Dunnett’s (compared to PBS group). * p < 0.05; ** p < 0.01; *** p < 0.001; **** p <0.0001. (b) Maximum weight loss recorded for each animal at any given timepoint after infection. Dots represent each mouse; data represented as violin plots with medians. One-way ANOVA with Dunnett’s (compared to PBS group); * p < 0.05; ** p < 0.01; *** p < 0.001.