Table 1.

Minimal inhibitory concentration (MIC) values determined for target compounds 3a–k and 4a–k in Staphylococcus aureus USA300 LAC* and Enterococcus species.

		MIC [µg/mL] a
Cpd.	R	Staphylococcus aureus	E. faecium	E. faecalis	E. casseliflavus
3a	H	8	128	16	>128
3b	5-Cl	4	8	16	8
3c	6-Cl	8	32	32	16
3d	5-Br	8	8	16	16
3e	6-Br	-	64	64	16
3f	5-CN	8	>128	32	128
3g	6-CN	4	>128	64	>128
3h	5-OH	2	16	16	64
3i	6-OH	2	8	16	32
3j	5-OBn	64	>128	128	64
3k	6-OBn	64	>128	128	128
4a	H	8	>128	16	>128
4b	5-Cl	4	8	8	8
4c	6-Cl	8	8	32	32
4e	6-Br	16	64	32	64
4f	5-CN	4	>128	32	>128
4g	6-CN	4	>128	128	>128
4h	5-OH	8	16	32	64
4i	6-OH	2	8	16	32
4j	5-OBn	64	>128	128	64
4k	6-OBn	32	>128	128	128
Oxacillin		1	-	-	-
Ciprofloxacin		-	-	4	-
Ampicillin		-	>128	2	-
Vancomycin		4	>128	128	32

^a Mean of three determinations.