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. 2019 Nov 23;7(4):195. doi: 10.3390/vaccines7040195

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Protection Against A/Nanchang/1/99 sublethal challenge. Mice were immunized with either 10⁸ or 10¹⁰ virus particles of recombinant Ad5-Mosaic, Ad5-A/PR/8/34, Ad5-Pdm09, 600 ng Fluzone, or PBS and challenged with 10^3.6 TCID₅₀ equivalents of mouse-adapted A/Nanchang/1/99 virus three weeks later (n = 5). Mice were monitored daily and humanely euthanized if 25% weight loss was recorded. (A,B) Weight loss for individual mice and (C,D) average weight loss are reported (data for average weight loss is reported as the mean with standard error).