Figure 2.

Relative gene expression related to fatty acid utilization and synthesis and inflammation. (a) Fold changes of mRNA expression of genes related to fatty acid synthesis. (b) Fold changes of mRNA expression of genes related to inflammation. Each bar or dot and error bar represents the mean±SD (n = 4). Rats consumed high-fat diets supplemented with (1) 50% ethanol blackberry leaf (450 mg/kg bw; BL), (2) 50% ethanol blackberry fruit extract (450 mg/kg bw; BF), (3) the mixture of blackberry leaf and fruit extracts (2:1; 150 mg/kg bw; BLF), (4) dextrin (450 mg/kg bw; NAFLD-C), and (5) milk thistle extracts (150 mg/kg bw; positive-control) for 12 weeks. Rats had low-fat diets (20 En% fat diet) containing 450 mg dextrin/kg bw as the normal-control group. ^a,b,c,d Bars with different letters were significantly different by Tukey’s test at P < 0.05.