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Immunohistochemistry (IHC) staining to detect histopathogenic lesions. Severe multifocal hemorrhages in the renal cortex of a suckling piglet (hematoxylin & eosin (HE); mag ×100) (A). Perivascular cuffing in the white matter of the cerebellum of a suckling piglet (HE; mag ×400) (B). Brown-stained viral antigens in the cryptal epithelium of the tonsil (IHC; mag ×400) (C). Brown-stained viral antigens in macrophages infiltrating the spleen (IHC; mag ×400) (D).
