Table 1.
The minimal inhibitory concentrations (MICs) and minimal bactericidal concentrations (MBCs) of sertraline (SER) against selected H. pylori strains.
| Strains | Antibiotic Resistance * | Activity of SER | |||
|---|---|---|---|---|---|
| MET | CLR | MIC ** | MBC ** | MBC/MIC Ratio | |
| J99 | S | S | 4 | 4 | 1 |
| Tx30a | S | S | 4 | 8 | 2 |
| 6237 | S | S | 4 | 4 | 1 |
| 7471 | S | S | 8 | 8 | 1 |
| 7189 | S | R | 4 | 8 | 2 |
| 7556 | S | R | 2 | 4 | 2 |
| 7388 | R | S | 4 | 4 | 1 |
| 7394 | R | S | 4 | 8 | 2 |
| 7143 | R | R | 2 | 8 | 4 |
| 7649 | R | R | 4 | 4 | 1 |
* Antibiotic resistance: S, Sensitive; R, Resistant; MET, Metronidazole; CLR, Clarithromycin. ** The MIC and MBC values are given in µg/mL.