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Flowchart of patient selections. * Indicate the time to appropriate antibiotic of >24 h. ** Included 235 patients with third-GCs, 154 with second-GCs, 24 with carbapenems, 60 with FQs, 30 with fourth-GCs, 21 with ampicillin/sulbactam, 13 with piperacillin/tazobactam, 3 with piperacillin, and 2 with others. ED = emergency department; GC = generation cephalosporin; FQ = fluoroquinolone; BLI = β-lactamase inhibitor.
