Table 2.

Genomic characteristics and putative virulence determinants of A. actinomycetemcomitans.

Genomic Characteristics and Putative Virulence Determinants of A. actinomycetemcomitans	References
Widespread colonization island or the tad locus	[67]
Autotransporter adhesins Aae, EmaA and Omp100/ApiA	[68,69,70]
A leukotoxin of the repeats in toxin (RTX) family with specificity for leukocytes	[71]
Growth-inhibitory factor cytolethal distending toxin	[72,73]
CagE, capable of inducing apoptosis	[74]
Dispersin B, a biofilm-releasing beta-hexosaminidase	[75]
Vesicle-independent extracellular release of proinflammatory lipoprotein	[76]