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. 2019 Dec 17;9(4):226. doi: 10.3390/diagnostics9040226
MPS Mucopolysaccharidoses
GAG glycosaminoglycan
ECM extracellular matrix
HS heparan sulfate
DS dermatan sulfate
ERT enzyme replacement therapy
HSCT hematopoietic stem cell therapy
FDA Food and Drug Administration
SRT substrate reduction therapy
PPS pentosan polysulfate
TLR4 toll-like receptor 4
TNF-α tumor necrosis factor-α
IL-1β interleukin-1β
IL-8 interleukin-8
MIP-1α macrophage inflammatory protein-1α
IL-6 interleukin-6
WBC white blood cell
AST aspartate aminotransferase
ALT alanine transaminase
APTT activated partial thromboplastin time
6MWT 6-minute walk test
3MSCT 3-minute stair climb test
ROM range of motion
UCG ultrasonic cardiography
MRI magnetic resonance imaging
CT computer tomography
ABR auditory brainstem response
LC-MS/MS liquid chromotraphy-tandem mass spectrometry
KS keratan sulfate
ELISA enzyme-linked immunosorbent assay
MIF macrophage migration inhibitory factor
VEGF vascular endothelial growth factor
IL-10 interleukin-10
IL-18 interleukin-18
MCP-1 macrophage migration inhibitory factor
TNFR1 tumor necrosis factor receptor 1
EEG electroencephalography
N/A not applicable
VC vital capacity
TD tidal volume
FEV1 forced expiratory volume per second
PEF peak expiratory flow
V.50 maxixmal flow rate of expiration at 50% vital capacity