MPS |
Mucopolysaccharidoses |
GAG |
glycosaminoglycan |
ECM |
extracellular matrix |
HS |
heparan sulfate |
DS |
dermatan sulfate |
ERT |
enzyme replacement therapy |
HSCT |
hematopoietic stem cell therapy |
FDA |
Food and Drug Administration |
SRT |
substrate reduction therapy |
PPS |
pentosan polysulfate |
TLR4 |
toll-like receptor 4 |
TNF-α |
tumor necrosis factor-α |
IL-1β |
interleukin-1β |
IL-8 |
interleukin-8 |
MIP-1α |
macrophage inflammatory protein-1α |
IL-6 |
interleukin-6 |
WBC |
white blood cell |
AST |
aspartate aminotransferase |
ALT |
alanine transaminase |
APTT |
activated partial thromboplastin time |
6MWT |
6-minute walk test |
3MSCT |
3-minute stair climb test |
ROM |
range of motion |
UCG |
ultrasonic cardiography |
MRI |
magnetic resonance imaging |
CT |
computer tomography |
ABR |
auditory brainstem response |
LC-MS/MS |
liquid chromotraphy-tandem mass spectrometry |
KS |
keratan sulfate |
ELISA |
enzyme-linked immunosorbent assay |
MIF |
macrophage migration inhibitory factor |
VEGF |
vascular endothelial growth factor |
IL-10 |
interleukin-10 |
IL-18 |
interleukin-18 |
MCP-1 |
macrophage migration inhibitory factor |
TNFR1 |
tumor necrosis factor receptor 1 |
EEG |
electroencephalography |
N/A |
not applicable |
VC |
vital capacity |
TD |
tidal volume |
FEV1 |
forced expiratory volume per second |
PEF |
peak expiratory flow |
V.50 |
maxixmal flow rate of expiration at 50% vital capacity |