Table 1.
Antibacterial activity of tested pharmacological agents (minimal inhibitory concentration values; (µg/mL)) *.
| Compounds | C. violaceum wt85 | C. violaceum CV026 | E. cloacae 31298 | S. paucimobilis Ezf 10-17 | Novosphingobium Spp. Rr 2-17 | S. marcescens AS-1 | E. coli ATCC 25922 | S. aureus ATCC 25923 |
|---|---|---|---|---|---|---|---|---|
| celecoxib | >250 | >250 | >250 | >250 | >250 | >250 | >250 | 15.6 |
| mebendazole | 62.5 | 62.5 | 125 | 62.5 | 62.5 | 31.3 | 125 | 62.5 |
| ivermectin | >250 | >250 | >250 | >250 | >250 | >250 | >250 | 31.3 |
| verapamil | >250 | >250 | >250 | 250 | 250 | >250 | >250 | 250 |
| promethazine | 31.3 | 31.3 | >250 | >250 | 250 | 125 | >250 | >250 |
| chlorpromazine | 15.6 | 15.6 | 125 | 62.5 | 62.5 | 62.5 | >250 | >250 |
| thioridazine | 15.6 | 15.6 | 62.5 | 31.3 | 31.3 | 15.6 | 31.3 | 125 |
| methotrexate | 125 | 125 | >250 | 125 | 125 | >250 | >250 | >250 |
| doxorubicin | 125 | 125 | 250 | 250 | 250 | 125 | 125 | 62.5 |
| bleomycin | 125 | 125 | 125 | 250 | 250 | >250 | 125 | 62.5 |
| atorvastatin | 125 | 125 | 31.3 | >250 | >250 | 125 | >250 | 62.5 |
| simvastatin | 250 | 250 | 62.5 | >250 | >250 | 125 | >250 | 125 |
| clotrimazole | >250 | >250 | >250 | >250 | >250 | >250 | >250 | 125 |
| fluconazole | >250 | >250 | >250 | >250 | >250 | >250 | >250 | 62.5 |
| DMSO | >2 V/V% | >2 V/V% | > 2 V/V% | >2 V/V% | >2 V/V% | >2 V/V% | >2 V/V% | >2 V/V% |
* Pharmacological agents not presented in this table had an MIC > 250 µg/mL for all tested bacterial strains.