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. 2019 Dec 3;7(4):204. doi: 10.3390/vaccines7040204

Figure 1.

Figure 1

Anti-E1/E2 IgG titers and Hepatitis C virus (HCV) neutralization activity in the serum of immunized mice. C57Bl/6 x Balb/c F1 mice (n = 10/group) were immunized intramuscular (i.m.) with HCV E1/E2 protein (1 µg) with or without adjuvant on days 0, 21, and 35. Serum was obtained from all mice on days 20 (A) and 42 (B) with serum analyzed for anti-E1/E2 IgG antibody by ELISA. Grouped data is presented as GMT + 95% CI. Serum from Day 42 was also tested for its ability to neutralize HCVpp entry into Huh7.5 liver cells in vitro (C). Meanings of the asterisks show in Section 2.8.