Skip to main content
. 2019 Nov 6;8(4):212. doi: 10.3390/antibiotics8040212

Table 1.

Antibacterial activities of berberine derivatives against PAGUg1931 and PAGUg1927.

Compound -R MIC of (µg/mL)
PAGUg1927 PAGUg1931
GM2 - 1024 8
Ber3 - >512 >512
1 -H 256 128
2 o-Br 256 128
3 p-Br 128 64
4 o-F 512 256
5 o-Cl 256 128
6 p-Cl 256 128
7 o-CH3 512 256
8 m-CH3 256 128
9 p-CH3 256 128
10 o-NO2 512 256
11 2,6-Cl 128 64

Note: R, side chain of the benzyl group of 13-benzylberberine derivatives; GM, gentamicin; Ber, berberine.