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. 2019 Nov 27;8(4):268. doi: 10.3390/pathogens8040268

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Histopathological analysis of meninges in PCN033-challenged mice with or without miR-19b-3p mimic pretreatment. (A) The normal meninges from uninfected mice (blue arrows). (B) The meninges from PCN033-challenged mice receiving the control mimics. Red arrows indicate meninges thickening, hyperemia, and inflammatory cell accumulation. (C) The meninges from PCN033-challenged mice receiving miR-19b-3p mimic pretreatment, and brown arrows show more severe thickening, hyperemia, and accumulation of inflammatory cells, as compared to the challenged brains with control mimic treatment. Scale bar = 200 μm.