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LipE profiling of (a) CYP1A2, (b) CYP2C9, (c) CYP2C19, (d) CYP2D6, and (e) CYP3A4 substrates. Data points labeled in red in LipE profiling plots indicate CYP450 substrates with metabolic stability between 0–4 (LipMetE) and optimal LipE values.
