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| analyte | nonbiotin-based assay (Architect/Abbott) | biotin-based assay (Roche) | bias (+) positive/(− negative) |
|---|---|---|---|
| progesterone | 0.4 nM | 125.4 nM | (+) 315-fold increase |
| FT4 | 11.3 pM | >100 pM | (+) >8.8-fold increase |
| TSH | 1.30 mIU/L | 0.02 mIU/L | (−) 65-fold decrease |
| FSH | 8.5 IU/L | 0.4 IU/L | (−) 21.3-fold decrease |
