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Cellular immune responses in human volunteers to intradermal injection of 80 μg mRNA (adapted from reference [34]). Intracellular cytokine staining of RABV-G-specific CD4+ T cells were analyzed using COMPASS and summarized as functionality (A) or polyfunctionality (B) scores. Boxes depict median values and IQRs, and whiskers extend from the hinge to the highest or lowest value within 1.5 × IQR of the respective hinge. N = 21 for days 0 and 42 and n = 15 for day 91.
