Skip to main content
. 2019 Oct 21;8(4):51. doi: 10.3390/antib8040051
Abbreviation Interpretation
AE adverse event
ALK anaplastic lymphoma kinase
APC antigen-presenting cell
ASCT autologous stem-cell transplantation
B2M beta-2-microglobulin
BTLA B and T lymphocyte attenuator
CAF cancer-associated fibroblast
CCR4 C-C chemokine receptor type 4
CD cluster of differentiation
CD40L CD40 ligand
cHL classical Hodgkin lymphoma
CR complete response
CRC colorectal cancer
CRR complete response rate
CSCC cervical squamous cell carcinoma
CSF-1 colony stimulating factor 1
CTLA-4 cytotoxic T-lymphocyte-associated protein 4
DLT dose-limiting toxicity
dMMR DNA mismatch repair-deficient
EGFR epidermal growth factor receptor
ER endoplasmic reticulum
FDA Food and Drug Administration
GAL9 galectin-9
GBM glioblastoma multiforme
GEJ gastroesophageal junction
GITR glucocorticoid-induced tumor necrosis factor receptor
HCC hepatocellular carcinoma
HL Hodgkin lymphoma
HLA human leukocyte antigen
HR hazard ratio
HVEM tumor necrosis factor receptor superfamily member 14
ICOS inducible T-cell co-stimulator
IDO indoleamine 2,3-dioxygenase
IFN interferon
IL interleukin
KIR killer cell immunoglobulin-like receptors
LAG-3 lymphocyte-activation gene-3
mAb monoclonal antibody
MCC Merkel cell carcinoma
M-CSF macrophage colony-stimulating factor
MDSC myeloid-derived suppressor cell
MHC major histocompatibility complex
MSI-H microsatellite instability-high
MTD maximum tolerated dose
MɸII type II macrophage
NK natural killer
NSCLC non-small cell lung cancer
NsqNSCLC non-squamous non-small cell lung cancer
ORR objective response rate
OS overall survival
OX40L OX40 ligand
PD-1 programmed cell death protein-1
PD-L1 programmed death-ligand 1
PD-L2 programmed death-ligand 2
PFS progression-free survival
PI3K phosphatidyl-inositol 3-kinase
PRR partial response rate
RCC renal cell carcinoma
rrPMBCL relapsed/refractory primary mediastinal B-cell lymphoma
SCLC small cell lung cancer
sqNSCLC squamous non-small cell lung cancer
TAP transporter associated with antigen processing
TCR T cell receptor
TGF-β transforming growth factor-beta
TIM-3 T cell immunoglobulin and mucin-domain containing-3
TME tumor microenvironment
TNBC triple-negative breast cancer
TNF tumor necrosis factor
Treg regulatory T cell
VEGF vascular endothelial growth factor