Table 1.
Baseline Characteristics of the Study Patients
| No pMI (n = 95) | pMI (n = 46) | P Value | |
|---|---|---|---|
| Age, yrs | 68 (61–74) | 67 (59–73) | 0.582 |
| Male | 83 (87) | 39 (85) | 0.793 |
| BMI, kg/m2 | 25 (22–27) | 24 (22–27) | 0.514 |
| Hypertension | 76 (80) | 35 (76) | 0.662 |
| Hyperlipidemia | 86 (91) | 42 (91) | 1.000 |
| Diabetes mellitus | 29 (31) | 12 (26) | 0.627 |
| Current smoker | 11 (12) | 7 (15) | 0.594 |
| Total cholesterol, mg/dL | 149 (134–173) | 160 (144–177) | 0.338 |
| LDL cholesterol, mg/dL | 82 (67–102) | 82 (71–100) | 0.811 |
| HDL cholesterol, mg/dL | 44 (38–52) | 46 (38–55) | 0.273 |
| Triglycerides, mg/dL | 135 (97–192) | 129 (94–167) | 0.356 |
| Hemoglobin A1c, % | 6.0 (5.6–6.3) | 5.9 (5.7–6.2) | 0.378 |
| Serum creatinine, mg/dL | 0.90 (0.79–1.05) | 0.93 (0.81–1.06) | 0.633 |
| Multivessel disease | 28 (29) | 18 (39) | 0.258 |
| Previous MI | 14 (15) | 10 (22) | 0.342 |
| LVEF, % | 60 (55–65) | 60 (57–65) | 0.732 |
| hs-cTnT before PCI, ng/mL |
0.008 (0.006–0.012) |
0.009 (0.006–0.016) |
0.543 |
| hs-cTnT after PCI, ng/mL |
0.027 (0.020–0.042) |
0.138 (0.094–0.276) |
< 0.001 |
| Medications | |||
| Statin | 88 (93) | 41 (89) | 0.527 |
| Beta-blocker | 67 (71) | 27 (59) | 0.185 |
| ACE inhibitor or ARB | 50 (53) | 24 (52) | 1.000 |
| MRI findings | |||
| 2D-PMR | 1.15 (0.98–1.36) | 1.66 (1.09–2.93) | < 0.001 |
| 3Di-PMR, PMR*mm3 | 9 (0–49.8) | 88.4 (32.2–203.7) | < 0.001 |
| Angiographic findings and PCI parameters | |||
| Mean reference vessel diameter (mm) | 3.50 (3.06–4.19) | 3.45 (3.07–4.24) | 0.852 |
| Ratio of the maximal balloon diameter to the vessel diameter | 0.95 (0.79–1.06) | 0.96 (0.83–1.06) | 0.852 |
| Total lesion length (mm) | 16 (10–26) | 18 (12–28) | 0.439 |
Values are medians (interquartile range) or n (%)
2D-PMR 2-dimensional plaque-to-myocardium signal intensity ratio, 3Di-PMR 3-dimensional integral of the plaque-to-myocardium signal intensity ratio, ACE Angiotensin-converting enzyme, ARB Angiotensin II receptor blocker, BMI Body mass index, HDL High-density lipoprotein, hs-cTnT High-sensitivity cardiac troponin T, LDL Low-density lipoprotein, LVEF Left ventricular ejection fraction, MI Myocardial infarction, MRI Magnetic resonance imaging, PCI Percutaneous coronary intervention, pMI Periprocedural myocardial injury, PMR*mm3 the unit of 3Di-PMR; defined as the integral of voxel volume multiplied by its PMR value > 1.0 from a coronary plaque