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. 2017 Aug 22;3(2):297–316. doi: 10.1007/s41030-017-0048-0

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0), which permits use, duplication, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — PRISMA flow diagram of study selection process. CDSR Cochrane Database of Systematic Reviews, CSR clinical study report, DARE Database of Abstracts of Reviews of Effects, GSK GlaxoSmithKline, HTA Health Technology Assessment, LABA long-acting β₂-agonist, LAMA long-acting muscarinic antagonist, NMA Network meta-analysis, SLR systematic literature review, TIO tiotropium