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. 2020 Jan 15;2020(1):hoz042. doi: 10.1093/hropen/hoz042

Table IV.

Prevalence of T2DM, use of antiglycemic drugs, lifestyle factors and biochemistry in women with PCOS and controls.

PCOS n = 27 Controls n = 94 P-value
T2DM, n (%) 5 (19) 1 (1) <0.01
Insulin treatment, n (%) 3 (11) 2 (2) 0.07
Metformin treatment, n (%) 3 (11) 1 (1) 0.03
Sedentary lifestyle, n (%) 18 (67) 57 (63) 0.82
Sedentary work, n (%) 23 (89) 79 (89) 1.00
mean ± SD median (range) mean ± SD median (range)
High fat diet 44 (9–104) 45 (0–125) 0.57
High sugar diet 6 (1–36) 9 (0–56) 0.01
Mediterranean diet 72 (26–261) 79 (18–293) 0.47
P-glucose (mmol/L) 6.0 ± 1.7 5.4 (5–13) 5.0 ± 1.0 4.8 (4–13) <0.01
S-insulin (mU/L) 14.1 ± 13.6 7.7 (3–52) 7.6 ± 5.7 6.4 (1–47) 0.07
HOMA-IR 4.5 ± 6.4 1.9 (0.8–29.6) 1.7 ± 1.5 1.4 (0.3–12.5) 0.02
S-SHBG (nmol/L) 66.1 ± 37.8 54.0 (25–178) 58.5 ± 25.7 57.1 (19.6–177.3) 0.70
S-testosterone (nmol/L) 1.01 ± 0.66 0.83 (0.40–2.70) 0.67 ± 0.27 0.62 (0.14–1.28) 0.06
FAI 2.2 ± 2.3 1.4 (0.3–10.8) 1.4 ± 1.0 1.1 (0.2–5.0) 0.40
OR of T2DM unadjusted OR CI (95%)
PCOS 21.14 2.35–190.14
BMI 1.45 1.17–1.80

High scores at the FFQ correspond to higher usage of that kind of food, high fat diet—possible score range, 0–630; high sugar diet—possible score range, 0–240; Mediterranean diet—possible score range, 0–540.

Significant P-values (<0.05) are marked as bold. Categorical comparisons were calculated using Fischer’s exact t-test. Intergroup comparisons of continuous variables that were normally distributed were tested with the independent samples Student’s t-test. Data that were not normally distributed were tested with the Mann–Whitney U test. ORs were computed with a multiple variate logistic regression analysis, to compare the relative impact of PCOS and BMI on T2DM diagnosis at follow-up.