Table IV.
PCOS n = 27 | Controls n = 94 | P-value | |||
---|---|---|---|---|---|
T2DM, n (%) | 5 (19) | 1 (1) | <0.01 | ||
Insulin treatment, n (%) | 3 (11) | 2 (2) | 0.07 | ||
Metformin treatment, n (%) | 3 (11) | 1 (1) | 0.03 | ||
Sedentary lifestyle, n (%) | 18 (67) | 57 (63) | 0.82 | ||
Sedentary work, n (%) | 23 (89) | 79 (89) | 1.00 | ||
mean ± SD | median (range) | mean ± SD | median (range) | ||
High fat diet | 44 (9–104) | 45 (0–125) | 0.57 | ||
High sugar diet | 6 (1–36) | 9 (0–56) | 0.01 | ||
Mediterranean diet | 72 (26–261) | 79 (18–293) | 0.47 | ||
P-glucose (mmol/L) | 6.0 ± 1.7 | 5.4 (5–13) | 5.0 ± 1.0 | 4.8 (4–13) | <0.01 |
S-insulin (mU/L) | 14.1 ± 13.6 | 7.7 (3–52) | 7.6 ± 5.7 | 6.4 (1–47) | 0.07 |
HOMA-IR | 4.5 ± 6.4 | 1.9 (0.8–29.6) | 1.7 ± 1.5 | 1.4 (0.3–12.5) | 0.02 |
S-SHBG (nmol/L) | 66.1 ± 37.8 | 54.0 (25–178) | 58.5 ± 25.7 | 57.1 (19.6–177.3) | 0.70 |
S-testosterone (nmol/L) | 1.01 ± 0.66 | 0.83 (0.40–2.70) | 0.67 ± 0.27 | 0.62 (0.14–1.28) | 0.06 |
FAI | 2.2 ± 2.3 | 1.4 (0.3–10.8) | 1.4 ± 1.0 | 1.1 (0.2–5.0) | 0.40 |
OR of T2DM | unadjusted OR | CI (95%) | |||
PCOS | 21.14 | 2.35–190.14 | |||
BMI | 1.45 | 1.17–1.80 |
High scores at the FFQ correspond to higher usage of that kind of food, high fat diet—possible score range, 0–630; high sugar diet—possible score range, 0–240; Mediterranean diet—possible score range, 0–540.
Significant P-values (<0.05) are marked as bold. Categorical comparisons were calculated using Fischer’s exact t-test. Intergroup comparisons of continuous variables that were normally distributed were tested with the independent samples Student’s t-test. Data that were not normally distributed were tested with the Mann–Whitney U test. ORs were computed with a multiple variate logistic regression analysis, to compare the relative impact of PCOS and BMI on T2DM diagnosis at follow-up.